LONDON Malcolm Brogdon Jersey , July 27 (Xinhua) -- A new drug developed at the University of Sheffield could become available to patients diagnosed with a wide range of cancers, the university said on Thursday.
Lynparza, the world's first and leading PARP inhibitor, is currently available for the treatment of some women with advanced BRCA2-related ovarian cancer.
In 2005, Professor Thomas Helleday and his team of researchers at the University of Sheffield demonstrated how PARP inhibitors could be used as a tailored treatment for patients with BRCA2 mutations Kareem Abdul-Jabbar Jersey , which are seen in both hereditary ovarian and breast cancer. PARP inhibitors work by blocking the cancer cell's ability to repair damage.
The discovery was patent protected and licensed to pharmaceutical company AstraZeneca, which continued the development process and undertook successful clinical trials. Now AstraZeneca and Merck & Co., Inc., have announced a global strategic oncology collaboration to co-develop and co-commercialize Lynparza for multiple cancer types.
"We welcome the announcement that AstraZeneca and Merck are working together to make this groundbreaking treatment available to more patients," said Professor Dave Petley Oscar Robertson Jersey , Vice-President for Research and Innovation at the University of Sheffield.
The drug will be developed as monotherapy and in combination with other potential medicines, further increasing the number of treatment options available for patients.
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CAIRO Khris Middleton Bucks Jersey , Aug. 6 (Xinhua) -- The recent increase of Egypt's foreign direct investments (FDI) amid the country's ongoing war against terrorism is a positive indicator that the Egyptian economic reform program is on the right track, said Egyptian economic experts.
The Egyptian ministry of investment said on Friday that FDI in Egypt rose by 26 percent to reach 8.7 billion U.S. dollars in the 20162017 fiscal year that ended in late June, compared to 6.9 billion dollars in the preceding fiscal year.
Economists still hope for further FDI to boost the country's economy that has been suffering over the past six years that witnessed massive political turmoil and relevant security issues, which led to declining tourism and foreign investment amid growing budget deficit, inflation rate and foreign and domestic debts.
"It is a very positive indicator. We hope this reflects on the gross domestic product Giannis Antetokounmpo Bucks Jersey , reduces unemployment and limits the budget deficit," Basant Fahmy, member of the parliament's economic committee, told Xinhua.
While Egypt is implementing a strict three-year economic reform program that includes austerity measures, energy subsidy cuts Jabari Parker Bucks Jersey , tax increase and a floating exchange rate, the country is engaged in a war against terrorism that killed hundreds of policemen and soldiers since the military removed former Islamist president Mohamed Morsi in July 2013.
Most of the anti-government terrorist attacks as well as those against the country's Coptic minority have been claimed by a Sinai-based group loyal to the regional Islamic State (IS) militant group.
Security campaigns also killed hundreds of militants and arrested a similar number of suspects as part of the country's anti-terror war declared by President Abdel-Fattah al-Sisi, who was then the army chief, following Morsi's ouster in response to mass protests.
Fahmy said that Egypt still needs further and faster foreign investments, arguing that they are below the desired level due to the general regional instability as well as the ongoing security conditions and counterterrorism war in Egypt.
"Investors care most about security and social stability Eric Bledsoe Bucks Jersey ," she explained.
"The FDI increase shows that Egypt is on the right track due to the laws for economic reform and fighting corruption in addition to the new investment law that lures investors," the lawmaker said, adding that the recent financial and monetary reforms would improve the investment climate in Egypt.
Egypt is planning to attract investments of about 30 billion dollars for its Suez Canal Economic Zone (SCZone) over the coming five years, according to a recent statement of the Egyptian investment minister.
The country is working hard to attract foreign businessmen to take part in its mega projects whether at the SCZone, or the currently under-construction new administrative capital city or other projects nationwide Khris Middleton Kids Jersey , reassuring investors about the noticeable improvement of security conditions in the most populous Arab country.
"The FDI increase is positive but still insufficient," said Yousry Tahoun, economics professor at Tanta University, pointing out that each terror operation that targets the police or the army greatly affects the FDI inflow.
Egypt struggles to fix its balance of trade, trying to increase local production and exports and reduce imports to boost economy.
Trade and Industry Minister Tarek Kabil announced earlier in August that the deficit in the country's balance of trade declined to 13 billion dollars in the first half of 2017 compared to 24 billion dollars in the same period in 2016 Giannis Antetokounmpo Kids Jersey , marking a 46-percent decrease in the trade balance deficit.
He added that in the same period imports also declined by 30 percent, from 34 billion dollars to 24 billion dollars, while exports increased